Type 2

Early Life Origins of Diabetes

Environmental exposure in early life have long-term impacts on the risk for diabetes development.

Pancreas Biology

Clusters of cells within the pancreas produce hormones such as insulin that control the levels of sugars in the bloodstream. Dysfunction in these cells leads to diabetes.

Interventions

We collaborate to translate our research findings into novel interventions that improve the wellness of children and their families affected by diabetes. We invite you to learn more about our ongoing projects.

Metabolism

The metabolic factors that contribute to type 2 diabetes development in youth may be different from those in adults. Through our interdisciplinary research we investigate how a wide range of metabolites and metabolic processes in a variety of organ systems.

Epigenetics

Environment exposures can impact the way genes work. Our team is investigating epigenetics to understand the mechanism and timing of biological embedding of exposures on long-term health.

Complications

Diabetes can lead to a range of complications including atherosclerosis, high blood pressure, kidney disease and blindness. Bringing together interdisciplinary researchers, we are advancing the understanding of the complex interactions between type 2 diabetes in youth and its complications.

Clinical Studies in Type 2 Diabetes

CLIMB

A pilot open-label randomized controlled trial of the Medtronic 770g in automode vs manual mode in people with type 1 diabetes postpartum.

CONCEPTT Kids

Using individuals from the CONCEPTT study, CONCEPTT Kids is assessing the association between mother’s blood glucose during pregnancy on their child’s IQ, social responsiveness, attention and language scores. Recruitment is from CONCEPTT enrollment.