Early Life Origins of Diabetes
Environmental exposure in early life have long-term impacts on the risk for diabetes development.
Clusters of cells within the pancreas produce hormones such as insulin that control the levels of sugars in the bloodstream. Dysfunction in these cells leads to diabetes.
We collaborate to translate our research findings into novel interventions that improve the wellness of children and their families affected by diabetes. We invite you to learn more about our ongoing projects.
The metabolic factors that contribute to type 2 diabetes development in youth may be different from those in adults. Through our interdisciplinary research we investigate how a wide range of metabolites and metabolic processes in a variety of organ systems.
Environment exposures can impact the way genes work. Our team is investigating epigenetics to understand the mechanism and timing of biological embedding of exposures on long-term healt.
Diabetes can lead to a range of complications including atherosclerosis, high blood pressure, kidney disease and blindness. Bringing together interdisciplinary researchers, we are advancing the understanding of the complex interactions between type 2 diabetes in youth and its complications.
Clinical Studies in Type 2 Diabetes
Basic Science Studies in Type 2 Diabetes
Learn how you can participate in our research projects
24-h ambulatory blood pressure readings and associations with albuminuria in youth with type 2 diabetes: A cross-sectional analysis from the iCARE cohort
24-hour ambulatory blood pressure monitors (ABPMs) are recommended for screening at risk children, however this test is not often used…
A new piece of the puzzle to explain how Type 1 Diabetes occurs and model the process in beta cells
A new study by CHRIM staff member and lead author Gabriel Brawerman in the lab of Dr. Peter Thompson has…
Tafazzin Deficiency Reduces Basal Insulin Secretion and Mitochondrial Function in Pancreatic Islets
Dr. Doucette, Dr. Dolinsky, and Dr. Hatch conducted a study to study the role of TAZ (Tafazzin), a cardiolipin (CL)…