Early Life Origins of Diabetes
Environmental exposure in early life have long-term impacts on the risk for diabetes development.
Pancreas Biology
Clusters of cells within the pancreas produce hormones such as insulin that control the levels of sugars in the bloodstream. Dysfunction in these cells leads to diabetes.
Interventions
We collaborate to translate our research findings into novel interventions that improve the wellness of children and their families affected by diabetes. We invite you to learn more about our ongoing projects.
Metabolism
The metabolic factors that contribute to type 2 diabetes development in youth may be different from those in adults. Through our interdisciplinary research we investigate how a wide range of metabolites and metabolic processes in a variety of organ systems.
Epigenetics
Environment exposures can impact the way genes work. Our team is investigating epigenetics to understand the mechanism and timing of biological embedding of exposures on long-term health.
Complications
Diabetes can lead to a range of complications including atherosclerosis, high blood pressure, kidney disease and blindness. Bringing together interdisciplinary researchers, we are advancing the understanding of the complex interactions between type 2 diabetes in youth and its complications.
Clinical Studies in Type 2 Diabetes
Basic Science Studies in Type 2 Diabetes
PREDISPOSE
Currently Recruiting
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Key Findings
All Articles
Cardiorespiratory Fitness and Physical Activity in Pediatric Diabetes
Are cardiorespiratory fitness (CRF) and physical activity lower among youths with diabetes compared with youths without diabetes? In this systematic…
Establishing evidence for immune surveillance of β-cell senescence
Cellular senescence is a programmed state of cell cycle arrest that involves a complex immunogenic secretome, eliciting immune surveillance and…
Factors Affecting Quality of Life in Adolescents Living with Type 2 Diabetes: A Sub study of The Improving renal Complications in Adolescents with type 2 diabetes through REsearch cohort
Type 2 diabetes (T2D) impacts adolescents living in challenging socioeconomic conditions disproportionately. However, impacts of T2D on quality of life…