Allison Dart MD, MSc
Assistant Professor and Pediatric Nephrologist
Department of Pediatrics & Child Health
Max Rady College of Medicine
Rady Faculty of Health Sciences
My research interests are in the epidemiology of chronic disease (CKD) in Indigenous children, with a current focus on renal outcomes in youth with type 2 diabetes. Currently the co-lead of the National iCARE study, funded by CIHR which will evaluate the bio-psychosocial determinants of albuminuria in youth with type 2 diabetes.
Vern Dolinsky PhD
Associate Professor
Department of Pharmacology & Therapeutics
Max Rady College of Medicine
Rady Faculty of Health Sciences
My research is focused on investigating the mechanisms involved in the development of gestational diabetes and how gestational diabetes contributes to the development of obesity, diabetes and related cardiovascular disease in youth. Our aim is to guide the development of novel therapies for obesity, diabetes and heart disease.
Michel Aliani PhD
Professor
Department of Food and Human Nutritional Sciences
Faculty of Agriculture and Food Sciences
My research is focused on mass spectrometry and NMR-based metabolomics studies of functional foods, drugs and their effect on biochemical pathways in populations with chronic diseases. Our goal is to provide healthy and acceptable foods to children and young adults and to understand the underlying mechanism related to the development of diabetes, renal and cardiovascular diseases.
Mandy Archibald BScN, PhD
Assistant Professor
Interdisciplinary Artist
College of Nursing
Rady Faculty of Health Sciences
My research lab leverages knowledge of lived experience through qualitative, mixed methods and arts-based research to improve care and social wellbeing. Through this emphasis on applied qualitative research and arts-based, collaborative knowledge translation, I seek to improve the relevance and impact of research for diverse stakeholder groups.
Christine Doucette PhD
Assistant Professor
Department of Physiology & Pathophysiology
Max Rady College of Medicine
Rady Faculty of Health Sciences
My research program aims to identify novel metabolic and molecular mechanisms that control the dynamic daily cycles of insulin secretion from the pancreatic beta cell, and to determine how exposure to various risk factors associated with type 2 diabetes impacts these daily cycles of insulin secretion.
Joe Gordon PhD
Associate Professor
Department of Human Anatomy & Cell Science
College of Nursing
Rady Faculty of Health Sciences
My program of research focuses on the regulation of mitochondrial function and metabolism during cardiac and skeletal muscle differentiation and remodeling, including disease related conditions such as diabetic cardiomyopathy, insulin resistance, and hypoxia/ischemia,; as well as physiological stimuli such as exercise and contractile activity. Specifically, my laboratory studies the transcriptional regulation and post-translational modification of the Bcl-2 family members Nix and Bnip3 utilizing both primary and immortalized cells, differentiated human induced pluripotent stem cells, and conditional knockout mice.
Grant Hatch PhD
Professor
Department of Pharmacology & Therapeutics
Max Rady College of Medicine
Rady Faculty of Health Sciences
My three main areas of research are 1) Biology of Cariolipin (CL): examining regulation of the metabolism CL, 2) Biology of Human Lipid Disorder: investigating the role of TAZ in CL metabolism and Barth Syndrome, 3) Biology of the Blood Brain Barrier: examining mechanisms that govern transport across human brain microvessel endothelial cells and the role that CL plays.
Meaghan Jones PhD
Assistant Professor
Department of Biochemistry & Medical Genetics
Max Rady College of Medicine
Rady Faculty of Health Sciences
My current focus is on the role of epigenetic changes in the link between environmental exposures in early life and later-onset chronic illness, including diabetes. Students and staff in my lab have the opportunity to use large epigenetic data sets from human birth cohort studies to discover epigenetic changes associated with specific environmental exposures. These findings inform further experiments using model systems to understand the molecular and developmental impacts of prenatal exposures, leading to a truly multi-disciplinary learning experience.
Lucy Marzban DMLS PhD
Associate Professor
College of Pharmacy
Rady Faculty of Health Sciences
My research program focuses on understanding why islet β-cells die in type 2 diabetes (T2D) and following transplantation in type 1 diabetes (T1D). Specifically, we aim to identify the cellular mechanisms by which protein aggregates called islet amyloid destroy β-cells in diabetes. The ultimate goal of our research is to develop new therapies to prevent or slow onset of T2D and enhance long-term survival of islet grafts in T1D.
Jon McGavock PhD
Associate Professor
Department of Pediatrics & Child Health
Max Rady College of Medicine
Rady Faculty of Health Sciences
My research program has 3 main pillars in order to span the spectrum of mechanistic human physiology studies to community-based participatory action research. Pillar 1: the determinants of type 2 diabetes and the associated complications, Pillar 2: dose of physical activity needed to prevent type 2 diabetes and improve metabolic control in individuals with type 1 diabetes, Pillar 3: the role of peer mentoring for the prevention and treatment of type 2 diabetes in youth.
Samantha Pauls PhD
Assistant Professor
College of Pharmacy
Rady Faculty of Health Sciences
My current research seeks to understand and target defects in immune cell metabolism that may contribute to the development or progression of obesity-associated metabolic diseases like type 2 diabetes and cardiovascular disease.
Ayesha Saleem PhD
Assistant Professor
Faculty of Kinesiology & Recreation Management (FKRM)
The main focus of my research program is to decipher intercellular signalling, as mediated by extracellular vesicles, that regulates the interplay between host tissue and imposed challenges. These challenges can be physiological (exercise, age), dysregulated metabolism-related (cancer, obesity, diabetes), or developmental (breastmilk).
Elizabeth Sellers MD, MSc
Professor and Pediatric Endocrinologist
Department of Pediatrics & Child Health
Max Rady College of Medicine
Rady Faculty of Health Sciences
My main areas of research focus are on pediatrics, endocrinology and metabolism, epidemiology, type 1 diabetes, type 2 diabetes, obesity, and metabolic syndrome.
Peter Thompson PhD
Assistant Professor
Department of Physiology & Pathophysiology
Max Rady College of Medicine
Rady Faculty of Health Sciences
My research focuses on understanding how pancreatic Beta cell stress responses and fate decisions drive the development of Type 1 Diabetes. We are seeking to elucidate the signaling pathways and cell fate changes in Beta cells that can be targeted to prevent and better treat this disease. Our studies in Type 1 Diabetes will also suggest new avenues of investigation for Type 2 Diabetes and obesity.
Brandy Wicklow MD, MSc
Associate Professor & Pediatric Endocrinologist
Department of Pediatrics & Child Health
Max Rady College of Medicine
Rady Faculty of Health Sciences
My research focus is on early life determinants of type 2 diabetes and renal disease in children and adolescents, with a particular interest in the impacts of the psychological, economic, and social impacts on wholistic health of all children living with diabetes. Current research is evaluating the fetal origins of childhood onset type 2 diabetes, including in utero and epigenetic modifications.
Jennifer Yamamoto MD, MSc
Assistant Professor
Department of Internal Medicine
Max Rady College of Medicine
Rady Faculty of Health Sciences
My research and clinical interest centre around diabetes in pregnancy. Specifically, my research program is interested in how we can leverage diabetes technology to improve outcomes in pregnancies complicated by type 1, type 2, and gestational diabetes.
Stephanie Manthanarack BSc
DREAM Research Coordinator
Department of Pediatrics & Child Health
Max Rady College of Medicine
Rady Faculty of Health Sciences
My research interests began with human nutritional sciences, specifically with dietary patterns that can prevent and treat chronic diseases, and innovative foods that can improve the health of individuals. I am fortunate to work with all of the DREAM researchers to help facilitate their research projects which span many different areas, but all have a common interest of improving the health of youth living with diabetes.