The iCARE (improving renal complications in adolescents with type 2 diabetes through research) study was designed to address the extremely high rates of early kidney damage in youth with type 2 diabetes. This study has recently expanded to include national cohorts, and the revised objects are; 1) Characterize the primary bio-psycho-social (BPS) risk factors associated with prevalent and progressive albuminuria, 2) Determine individual, family and community level factors that influence biological and psychological risk factors and behaviours (adherence) that could be modified to protect against prevalent and progressive albuminuria, 3) Determine if systemic renal inflammation is the common pathway through which BPS risk factors lead to albuminuria in youth with type 2 diabetes.
National iCARE sites
iCARE abstracts 2017
The iCARE Participant Advisory Group was created in 2015. The iCARE participant advisory group (PAG) has become integral to the iCARE study. Made up of adolescents and caregivers living with type 2 diabetes, this advisory group has contributed to the methodology and data collection of the study by introducing the importance of collecting mental health data and how this information could be captured within the study. Identifying shame, isolation and stigma as barriers towards self-management, mental health has been recognized as an important priority within iCARE:
"The advisory group is really critical to ensure that mental health is a component throughout. They give us a lot of feedback about the measures that we use to help us decide which ones we should be using and what's appropriate."
Dr. Allison Dart (co-investigator for iCARE)