DREAM UPDATES

Time to Implement the Kidney Failure Risk Equation Into Pediatric Practice

Dr. Allison Dart published in JAMA Pediatrics about the increasing prevalence of Chronic Kidney Disease (CKD) in the pediatric population. The results from this validation study have the potential to change clinical practices when estimating 1-2 year risk of kidney failure in youth. CLICK HERE to view the article.

Irisin may explain why some teens benefit from exercise, while others do not.

Former DREAM trainee Dr. Martin Senechal discovers that a muscle protein may explain why some teens benefit from exercise, while others don’t. It’s well established that the benefits of exercise can vary greatly between different people. For example, among the group overweight adolescents involved in the 6-month POWER trial; we found that on average exercise training led to improvements in fitness and modest changes in body composition compared to those that did not exercise. However, the individual response to exercise varied dramatically. Some children lost 10kg of fat mass while others gained 6kg (Figure 2). The mechanisms underlying these individual responses to exercise are not entirely

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